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Literature summary for 3.4.24.56 extracted from

  • Vepsaelaeinen, S.; Parkinson, M.; Helisalmi, S.; Mannermaa, A.; Soininen, H.; Tanzi, R.E.; Bertram, L.; Hiltunen, M.
    Insulin-degrading enzyme is genetically associated with Alzheimers disease in the Finnish population (2007), J. Med. Genet., 44, 606-608.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
IDE gene is localized on chromosome 10q24, genotyping of IDE in the Finnish population, overview Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information genotyping of single nucleotide polymorphisms in the IDE gene in Finnish patients with Alzheimer's disease, SNPs rs4646953 and rs4646955 to be associated with Alzheimer's disease, the insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
insulin + H2O Homo sapiens degradation ?
-
?
additional information Homo sapiens the insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
Finnish population
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
insulin + H2O degradation Homo sapiens ?
-
?
additional information the insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
IDE
-
Homo sapiens
Insulin-degrading enzyme
-
Homo sapiens