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Literature summary for 3.4.24.56 extracted from

  • Song, E.S.; Hersh, L.B.
    Insulysin: an allosteric enzyme as a target for Alzheimers disease (2005), J. Mol. Neurosci., 25, 201-206.
    View publication on PubMed
Search for more literature for 3.4.24.56

Activating Compound

Activating Compound Comment Organism Structure
bradykinin activation of reaction with substrate 2-aminobenzoyl-GGFLRKHGQ-(N-(2,4-dinitrophenyl)ethylenediamine) and amyloid beta-protein Mus musculus
dynorphin A-17 activation of reaction with substrate 2-aminobenzoyl-GGFLRKHGQ-(N-(2,4-dinitrophenyl)ethylenediamine) and amyloid beta-protein Mus musculus
dynorphin B-13 activation of reaction with substrate 2-aminobenzoyl-GGFLRKHGQ-(N-(2,4-dinitrophenyl)ethylenediamine) and amyloid beta-protein Mus musculus
dynorphin B-9 activation of reaction with substrate 2-aminobenzoyl-GGFLRKHGQ-(N-(2,4-dinitrophenyl)ethylenediamine) and amyloid beta-protein Mus musculus
Insulin B-chain activation of reaction with substrate 2-aminobenzoyl-GGFLRKHGQ-(N-(2,4-dinitrophenyl)ethylenediamine) and amyloid beta-protein Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information with substrate 2-aminobenzoyl-GGFLRKHGQ-(N-(2,4-dinitrophenyl)ethylenediamine), enzyme exhibits allosteric kinetics Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 enzyme-deficient strain
-

Source Tissue

Source Tissue Comment Organism Textmining
brain in enzyme-deficient strain, accumulation of amyloid beta-protein Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aminobenzoyl-GGFLRKHGQ-(N-(2,4-dinitrophenyl)ethylenediamine) + H2O
-
 Mus musculus ?
-
 ?