Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | isoform generated by translation of enzyme at an in-frame initiation codon 123 nucleotides upstream of the canonical translation start site, resulting in addition of a 41 amino acid N-terminal mitochondrial targeting sequence | Homo sapiens | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme can degrade cleaved mitochondrial targeting sequences, role of enzyme within mitochondria | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | for the mitochondrial isoform, mitochondrial targeting sequence of 41 amino acids is probably removed upon import into mitochondria | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme can degrade cleaved mitochondrial targeting sequences, role of enzyme within mitochondria | Homo sapiens | ? | - |
? | |
peptide containing the mitochondrial targeting sequence of E1alpha subunit of human pyruvate dehydrogenase + H2O | hydrolysis occurs at several sites | Homo sapiens | ? | - |
? |