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Literature summary for 3.4.24.54 extracted from
- Characterization of mucrotoxin A from the venom of Trimeresurus mucrosquamatus (the Chinese habu snake) (1985), Toxicon, 23, 637-645.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Protobothrops mucrosquamatus | produces hemorrhage in heart and stomach | ? | - |
? |  |
| additional information | Protobothrops mucrosquamatus | lethal and hemorrhagic toxin | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Protobothrops mucrosquamatus | - |
Chinese habu snake | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| from lyophilized crude venom | Protobothrops mucrosquamatus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom | - |
Protobothrops mucrosquamatus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Ala-Leu + H2O | less effective than Gly-Pro, Leu-Gly or Gly-Leu | Protobothrops mucrosquamatus | Alanine + leucine | - |
? | |
| Dimethylcasein + H2O | - |
Protobothrops mucrosquamatus | ? | - |
? | |
| Fibrinogen + H2O | hydrolyzes first the Aalpha and then the Bbeta chain | Protobothrops mucrosquamatus | Hydrolyzed fibrinogen | - |
? | |
| Gly-Gly + H2O | less effective than Gly-Pro, Leu-Gly or Gly-Leu | Protobothrops mucrosquamatus | Glycine + glycine | - |
? | |
| Gly-Leu + H2O | - |
Protobothrops mucrosquamatus | Glycine + leucine | - |
? | |
| Gly-Met + H2O | less effective than Gly-Pro, Leu-Gly or Gly-Leu | Protobothrops mucrosquamatus | glycine + L-methionine | - |
? | |
| Gly-Pro + H2O | - |
Protobothrops mucrosquamatus | Glycine + proline | - |
? | |
| Gly-Tyr + H2O | less effective than Gly-Pro, Leu-Gly or Gly-Leu | Protobothrops mucrosquamatus | Glycine + tyrosine | - |
? | |
| His-Leu + H2O | less effective than Gly-Pro, Leu-Gly or Gly-Leu | Protobothrops mucrosquamatus | Histidine + leucine | - |
? | |
| Leu-Gly + H2O | - |
Protobothrops mucrosquamatus | Leucine + glycine | - |
? | |
| Leu-Tyr + H2O | less effective than Gly-Pro, Leu-Gly or Gly-Leu | Protobothrops mucrosquamatus | Leucine + tyrosine | - |
? | |
| additional information | no substrate: casein, exhibits lethal and hemorrhagic activity | Protobothrops mucrosquamatus | ? | - |
? | |
| additional information | produces hemorrhage in heart and stomach | Protobothrops mucrosquamatus | ? | - |
? | |
| additional information | lethal and hemorrhagic toxin | Protobothrops mucrosquamatus | ? | - |
? | |
| Oxidized insulin B-chain + H2O | cleavage at Ser9-His10, His10-Leu11, Ala14-Leu15, Leu15-Tyr16 and Tyr16-Leu17 | Protobothrops mucrosquamatus | Hydrolyzed insulin B-chain | - |
? | |
| Tyr-Leu + H2O | less effective than Gly-Pro, Leu-Gly or Gly-Leu | Protobothrops mucrosquamatus | Tyrosine + leucine | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Protobothrops mucrosquamatus |
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