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Literature summary for 3.4.24.50 extracted from

  • Tanizaki, M.M.
    Bothrolysin (2004), Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press, 1, 657-658.
No PubMed abstract available
Search for more literature for 3.4.24.50

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline totally inhibits at 0.1 mM Bothrops jararaca
DM43 serum from opossum, inhibits the fibrinogenolytic activity of bothrolysin and forms a stable complex with it Bothrops jararaca
DTNB inhibitory, partially prevented by addition of Ca2+ Bothrops jararaca
EDTA totally inhibits at 0.1 mM Bothrops jararaca
additional information not inhibited by phosphoramidon at 0.5 mM and E-64 and its derivates Bothrops jararaca
Protein inhibitor from blood plasma of Bothrops jararaca, completely inhibits Bothrops jararaca

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ increases reaction velocity, half-maximum activation at 0.4 mM Bothrops jararaca

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
23000
-
-
 Bothrops jararaca

Organism

Organism UniProt Comment Textmining
Bothrops jararaca
-
-
-

Purification (Commentary)

Purification (Comment) Organism
by column chromatography Bothrops jararaca

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
 Bothrops jararaca
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin I + H2O
-
 Bothrops jararaca Asp-Arg-Val-Tyr-Ile-His-Pro + Phe-His-Leu
-
 ?
casein + H2O
-
 Bothrops jararaca ?
-
 ?
insulin B chain + H2O
-
 Bothrops jararaca FVNQ + HLCGS + HLVEA + LYLVCGERGFFYTPKA
-
 ?

Synonyms

Synonyms Comment Organism
J Protease
-
 Bothrops jararaca