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Literature summary for 3.4.24.45 extracted from

  • Fox, J.W.; Bjarnason, J.B.
    Atrolysin F (2004), Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press, 1, 676-677.
No PubMed abstract available

Application

Application Comment Organism
medicine second-most potent hemorrhagic toxin of all the atrolysins, systemic hemorrhage in lung, kidney, liver, heart, destruction of muscle tissue Crotalus atrox

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline inhibits proteolytic activity Crotalus atrox
EDTA inhibits proteolytic activity Crotalus atrox

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ 1.15 mol per mol enzyme Crotalus atrox

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64000
-
SDS-PAGE Crotalus atrox

Organism

Organism UniProt Comment Textmining
Crotalus atrox
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ion-exchange chromatography and gel filtration Crotalus atrox

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Crotalus atrox
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Dimethylcasein + H2O
-
Crotalus atrox ?
-
?
Fibrinogen + H2O
-
Crotalus atrox ?
-
?
Oxidized insulin B-chain + H2O
-
Crotalus atrox ?
-
?

Subunits

Subunits Comment Organism
monomer
-
Crotalus atrox

Synonyms

Synonyms Comment Organism
Hemorrhagic toxin f
-
Crotalus atrox
HT-f
-
Crotalus atrox