Cloned (Comment) | Organism |
---|---|
- |
Crotalus atrox |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Crotalus atrox | |
EDTA | - |
Crotalus atrox |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc metalloproteinase, 1 mol zinc/mol enzyme | Crotalus atrox |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
64000 | - |
1 * 64000, Crotalus atrox, SDS-PAGE | Crotalus atrox |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Basement membranes surrounding capillaries + H2O | Crotalus atrox | involved in disruption of capillary membranes | ? | - |
? | |
Basement membranes surrounding capillaries + H2O | Crotalus atrox | together with atrolysin A member of the class P-III hemorrhagic toxins | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Crotalus atrox | - |
Western diamondback rattlesnake | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
no glycoprotein | - |
Crotalus atrox |
Purification (Comment) | Organism |
---|---|
from lyophilized crude venom | Crotalus atrox |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Crotalus atrox | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Basement membrane preparation + H2O | - |
Crotalus atrox | ? | - |
? | |
Basement membranes surrounding capillaries + H2O | involved in disruption of capillary membranes | Crotalus atrox | ? | - |
? | |
Basement membranes surrounding capillaries + H2O | together with atrolysin A member of the class P-III hemorrhagic toxins | Crotalus atrox | ? | - |
? | |
Collagen IV + H2O | basement membrane component | Crotalus atrox | ? | - |
? | |
Fibrinogen + H2O | cleaves gamma-chain, Aalpha and Bbeta-chains remain intact | Crotalus atrox | Hydrolyzed fibrinogen | - |
? | |
Fibronectin + H2O | - |
Crotalus atrox | ? | - |
? | |
Gelatin of collagen type I + H2O | - |
Crotalus atrox | ? | - |
? | |
Gelatin of collagen type III + H2O | - |
Crotalus atrox | ? | - |
? | |
Gelatin of collagen type IV + H2O | - |
Crotalus atrox | ? | - |
? | |
Laminin + H2O | basement membrane component | Crotalus atrox | ? | - |
? | |
additional information | - |
Crotalus atrox | ? | - |
? | |
Nidogen + H2O | basement membrane component | Crotalus atrox | ? | - |
? | |
Oxidized insulin B-chain + H2O | - |
Crotalus atrox | Hydrolyzed oxidized insulin B-chain | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 64000, Crotalus atrox, SDS-PAGE | Crotalus atrox |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
pI: 7.7 | Crotalus atrox |