Application | Comment | Organism |
---|---|---|
medicine | the endoplasmic reticulum and the Golgi hinderes the exit of GP63 metalloprotease from the parasitophorous vacuole and dampens the cleavage of host proteins by GP63 | Leishmania major |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | the host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole. The enzyme is released from the parasite surface following phagocytosis and is redistributed to the endoplasmic reticulum of macrophages | Leishmania major | - |
- |
vacuole | the host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole | Leishmania major | 5773 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania major | P08148 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
promastigote | - |
Leishmania major | - |
Synonyms | Comment | Organism |
---|---|---|
GP63 metalloprotease | - |
Leishmania major |