Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Leishmania amazonensis | 16020 | - |
membrane | glycosylphosphatidylinositol-anchored | Leishmania major | 16020 | - |
soluble | Leishmania mexicana amastigotes | Leishmania amazonensis | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | zinc containing metalloproteinase | Leishmania amazonensis | |
Zinc | zinc containing metalloproteinase | Leishmania major | |
Zinc | zinc containing metalloproteinase | Leishmania infantum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Leishmania amazonensis | - |
- |
- |
Leishmania infantum | - |
- |
- |
Leishmania major | - |
infective strain LV39 | - |
Leishmania major | - |
non-infective strains LEM513 | - |
Leishmania major | - |
non-infective strains LRC-119 | - |
Purification (Comment) | Organism |
---|---|
lipophosphoglycan deficient LRC-L119 promastigotes | Leishmania major |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
amastigote | - |
Leishmania amazonensis | - |
promastigote | - |
Leishmania amazonensis | - |
promastigote | - |
Leishmania major | - |
promastigote | - |
Leishmania infantum | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Ala-Arg-Ser-Val-Val-Arg-Asp-Val-Asn + H2O | i.e. synthetic peptide derived from leishmanolysin | Leishmania major | Ala-Arg-Ser-Val + Val-Arg-Asp-Val-Asn | - |
? | |
azocasein + H2O | - |
Leishmania major | low molecular weight acid-soluble azopeptides | - |
? | |
Casein micelles + H2O | milk assay | Leishmania major | ? | - |
? | |
Dansyl-Ala-Tyr-Leu-Lys-Lys-Trp-Val-NH2 + H2O | cleavage site: Tyr-Leu | Leishmania major | Dansyl-Ala-Tyr + ? | - |
? | |
Elastin + H2O | zymographic assay | Leishmania major | ? | - |
? | |
Fibrinogen + H2O | - |
Leishmania amazonensis | ? | - |
? | |
Fibrinogen + H2O | ovine fibrinogen, zymographic assay | Leishmania major | ? | - |
? | |
Glucagon + H2O | - |
Leishmania major | ? | - |
? | |
Leu-Ile-Ala-Tyr-Leu-Lys-Lys-Ala-Thr + H2O | from horse cytochrome | Leishmania major | Leu-Ile-Ala-Tyr + ? | - |
? | |
Leu-Ile-Ala-Tyr-Ser-Lys-Lys-Ala-Thr + H2O | from horse cytochrome | Leishmania major | ? | - |
? | |
additional information | specificity is defined by P'-subsites of the substrates | Leishmania major | ? | - |
? | |
Oxidized insulin B-chain + H2O | - |
Leishmania major | ? | - |
? | |
Peptide 170-182 from CW-3 HLA antigen + H2O | - |
Leishmania major | ? | - |
? | |
Peptide 83-94 from beta-chain of HLA DO + H2O | - |
Leishmania major | ? | - |
? | |
Peptide 97-105 from Leishmanolysin + H2O | - |
Leishmania major | ? | - |
? | |
Peptides from horse cytochrome c + H2O | i.e. peptides 1-25, 39-53 and 81-104 | Leishmania major | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Leishmania amazonensis |
37 | - |
assay at | Leishmania major |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | 6 | soluble amastigote enzyme, Leishmania mexicana | Leishmania major |