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Literature summary for 3.4.24.35 extracted from

  • Reiss, M.J.; Han, Y.P.; Garcia, E.; Goldberg, M.; Yu, H.; Garner, W.L.
    Matrix metalloproteinase-9 delays wound healing in a murine wound model (2010), Surgery, 147, 295-302.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
4-aminophenylmercuric acetate
-
Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in immortalized keratinocytes, transduced by lentivrus Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
collagen type IV + H2O
-
Homo sapiens ?
-
?
Gelatin + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
matrix metalloproteinase-9
-
Homo sapiens
MMP-9
-
Homo sapiens

General Information

General Information Comment Organism
physiological function MMP-9 directly delays wound healing through interference with re-epithelialization, MMP-9 interferes with the basement membrane protein structure, which in turn impedes keratinocyte migration, attachment, and the reestablishment of the epidermis Homo sapiens