Literature summary for 3.4.24.35 extracted from

Wagner, S.; Breyholz, H.J.; Hoeltke, C.; Faust, A.; Schober, O.; Schaefers, M.; Kopka, K.
A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies (2009), Appl. Radiat. Isot., 67, 606-610.

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Inhibitors

Inhibitors	Comment	Organism	Structure
(R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyphenyl-sulfonamido)-N-hydroxy-3-methylbutanamide	-	Mus musculus
CGS 27023A	-	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Synonyms

Synonyms	Comment	Organism
gelatinase B	-	Mus musculus
matrix metalloproteinase-9	-	Mus musculus
MMP-9	-	Mus musculus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0000005	-	-	Mus musculus	(R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyphenyl-sulfonamido)-N-hydroxy-3-methylbutanamide
0.000006	-	-	Mus musculus	CGS 27023A

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Release 2023.1 (January 2023)