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Literature summary for 3.4.24.35 extracted from

  • Soeder, S.; Roach, H.I.; Oehler, S.; Bau, B.; Haag, J.; Aigner, T.
    MMP-9/gelatinase B is a gene product of human adult articular chondrocytes and increased in osteoarthritic cartilage (2006), Clin. Exp. Rheumatol., 24, 302-304.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
interleukin-1beta
-
Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
fibrillar collagen + H2O Homo sapiens degradation, MMP-9 is involved in development of osteoarthritis, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cartilage from femoral condyles in the knee Homo sapiens
-
chondrocyte articular chondrocyte of the late-stage osteoarthritis cartilage with surface fibrillation and chondrocyte clusters, not in healthy chondrocytes, overview Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
fibrillar collagen + H2O degradation, MMP-9 is involved in development of osteoarthritis, overview Homo sapiens ?
-
?
fibrillar collagen + H2O degradation, cleavage within the triple helix Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
MMP-9
-
Homo sapiens