Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | MMP-9 is upregulated by tumor necrosis factor alpha, TNFalpha | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | MMP-9-deficient mice show eliminated elastin breakdown in coronary artery in the Kawasaki disease | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Mus musculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Elastin + H2O | Mus musculus | MMP-9 activity leads to elastin breakdown in an animal model of Kawasaki disease, a multisystem vasculitis leading to damage in the coronary circulationand aneurysm formation, overview | ? | - |
? | |
Gelatin + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
C57BL/6, FVB/NJ, or MMP-9-/-, with FVB/NJ background, mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
coronary artery | coronary arteritis is induced by Lactobacillus casei cell wall extract injection | Mus musculus | - |
heart | enzyme activity and expression analysis, overview | Mus musculus | - |
vascular smooth muscle cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Elastin + H2O | - |
Mus musculus | ? | - |
? | |
Elastin + H2O | MMP-9 activity leads to elastin breakdown in an animal model of Kawasaki disease, a multisystem vasculitis leading to damage in the coronary circulationand aneurysm formation, overview | Mus musculus | ? | - |
? | |
Gelatin + H2O | - |
Mus musculus | ? | - |
? | |
Gelatin + H2O | gelatin zymography | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Matrix metalloproteinase 9 | - |
Mus musculus |
MMP-9 | - |
Mus musculus |