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Literature summary for 3.4.24.24 extracted from

  • Lesniak-Walentyn, A.; Hrabia, A.
    Expression and localization of matrix metalloproteinases (MMP-2, -7, -9) and their tissue inhibitors (TIMP-2, -3) in the chicken oviduct during maturation (2016), Cell Tissue Res., 364, 185-197 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene MMP2, quantitative RT-PCR enzyme expression analysis Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Gallus gallus
-
-
additional information enzyme localization and comparison to other MMPs, immunohistochemic analysis Gallus gallus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ metalloproteinase Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gelatin + H2O Gallus gallus
-
?
-
?
Gelatin + H2O Gallus gallus Hy-Line Brown
-
?
-
?

Organism

Organism UniProt Comment Textmining
Gallus gallus Q90611
-
-
Gallus gallus Hy-Line Brown Q90611
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information quantitative enzyme tissue expression analysis in the chicken oviduct during maturation Gallus gallus
-
oviduct infundibulum, magnum, isthmus, and shell gland. Developmental changes, overview Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gelatin + H2O
-
Gallus gallus ?
-
?
Gelatin + H2O
-
Gallus gallus Hy-Line Brown ?
-
?

Subunits

Subunits Comment Organism
? x * 72000, enzyme proform, SDS-PAGE, x * 66000, mature active enzyme, SDS-PAGE Gallus gallus

Synonyms

Synonyms Comment Organism
gelatinase
-
Gallus gallus
MMP-2
-
Gallus gallus

General Information

General Information Comment Organism
physiological function potential role of the MMP system in avian oviduct development, avian reproductive system differs from that of mammals. The gelatinases, stromelysins and matrilysins, all belonging to the MMP family, are capable of degrading major constituents of basement membranes, including type IV collagen, laminin and fibronectin. Gelatinolytic activity of MMPs in the chicken oviduct during maturation, overview Gallus gallus