Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ascorbic acid | - |
Sus scrofa | |
GSH | - |
Homo sapiens | |
GSH | - |
Sus scrofa | |
GSSG | - |
Homo sapiens | |
GSSG | - |
Sus scrofa | |
L-ascorbic acid | - |
Homo sapiens | |
L-cysteine | - |
Homo sapiens | |
L-cysteine | - |
Sus scrofa | |
L-histidine | - |
Homo sapiens | |
L-histidine | - |
Sus scrofa | |
L-homocysteine | - |
Homo sapiens | |
L-homocysteine | - |
Sus scrofa | |
L-methionine | - |
Homo sapiens | |
L-methionine | - |
Sus scrofa | |
additional information | inhibition potency of sulfur-containing compounds, overview | Homo sapiens | |
additional information | inhibition potency of sulfur-containing compounds, overview | Sus scrofa | |
N-acetylcysteine | - |
Homo sapiens | |
N-acetylcysteine | - |
Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Sus scrofa | - |
newborn undergoing hypoxia and reoxygenation | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | low activity | Sus scrofa | - |
commercial preparation | recombinant enzyme | Homo sapiens | - |
left ventricle | - |
Sus scrofa | - |
liver | - |
Sus scrofa | - |
lung | high activity | Sus scrofa | - |
additional information | MMP-2 activity in tissues taken from newborn piglets undergoing hypoxia and reoxygenation, overview | Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | gelatin zymography | Homo sapiens | ? | - |
? | |
Gelatin + H2O | gelatin zymography | Sus scrofa | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MMP-2 | - |
Homo sapiens |
MMP-2 | - |
Sus scrofa |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.061 | - |
recombinant enzyme | Homo sapiens | L-cysteine | |
0.118 | - |
recombinant enzyme | Homo sapiens | L-histidine | |
0.141 | - |
recombinant enzyme | Homo sapiens | ascorbic acid | |
0.195 | - |
recombinant enzyme | Homo sapiens | GSH | |
0.547 | - |
recombinant enzyme | Homo sapiens | GSSG | |
0.727 | - |
recombinant enzyme | Homo sapiens | L-homocysteine | |
1 | - |
recombinant enzyme | Homo sapiens | N-acetylcysteine | |
8.68 | - |
recombinant enzyme | Homo sapiens | L-methionine |