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Literature summary for 3.4.24.24 extracted from

  • Briknarova, K.; Grishaev, A.; Banyai, L.; Tordai, H.; Patthy, L.; Llinas, M.
    The second type II module from human matrix metalloproteinase 2: structure, function and dynamics (1999), Structure, 7, 1235-1245.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
membrane-type 1 matrix metalloproteinase activity in the extracellular environment is modulated by this activator Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
second fibronectin type II module, residues 278-336, produced in Escherichia coli Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens important role in extracellular matrix degradation during cell migration and tissue remodeling, involved in development, inflammation, wound healing, tumor invasion, metastasis and other physiological and pathological processes ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
human
-

Purification (Commentary)

Purification (Comment) Organism
second fibronectin type II module, residues 278-336, produced in Escherichia coli Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Collagen + H2O
-
Homo sapiens ?
-
?
Elastin + H2O
-
Homo sapiens ?
-
?
Fibronectin + H2O
-
Homo sapiens ?
-
?
Laminin + H2O
-
Homo sapiens ?
-
?
additional information important role in extracellular matrix degradation during cell migration and tissue remodeling, involved in development, inflammation, wound healing, tumor invasion, metastasis and other physiological and pathological processes Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
72 kDa type IV collagenase
-
Homo sapiens
gelatinase A
-
Homo sapiens
human matrix metalloproteinase 2
-
Homo sapiens
MMP-2
-
Homo sapiens