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Literature summary for 3.4.24.24 extracted from

  • Feng, Y.; Likos, J.J.; Zhu, L.; Woodward, H.; Munie, G.; McDonald, J.J.; Stevens, A.M.; Howard, C.P.; De Crescenzo, G.A.; Welsch, D.; Shieh, H.S.; Stallings, W.C.
    Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor (2002), Biochim. Biophys. Acta, 1598, 10-23.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
p-aminophenyl-mercuric acetate
-
Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
truncated MMP-2 catalytic domain MMP-2C Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
-
Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
SC-74020 hydroxamic acid inhibitor Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc-dependent Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens implicated in tumor cell metastasis and angiogenesis ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
human
-

Purification (Commentary)

Purification (Comment) Organism
truncated MMP-2 catalytic domain MMP-2C Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibronectin + H2O
-
Homo sapiens ?
-
?
additional information implicated in tumor cell metastasis and angiogenesis Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
gelatinase A
-
Homo sapiens
matrix metalloproteinase-2
-
Homo sapiens