Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.23 extracted from

  • Huang, Y.; Yu, H.; Lei, H.; Xie, C.; Zhong, Y.
    Matrix metalloproteinase 7 is a useful marker for 5-fluorouracil-based adjuvant chemotherapy in stage II and stage III colorectal cancer patients (2014), Med. Oncol., 31, 824.
    View publication on PubMed
Search for more literature for 3.4.24.23

Application

Application Comment Organism
diagnostics matrix metalloproteinase 7 is a useful marker for 5-fluorouracil-based adjuvant chemotherapy in stage II and stage III colorectal cancer patients Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm the enzyme is expressed in the cytoplasm in colorectal cancer cells Homo sapiens 5737
-
extracellular
-
 Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ a zinc metalloprotease Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P09237 gene MMP7
-

Source Tissue

Source Tissue Comment Organism Textmining
colon cancer cell MMP7 is secreted mainly by tumor cells instead of matrix cells in colorectal cancer Homo sapiens
-
colorectal cancer cell MMP7 is secreted mainly by tumor cells instead of matrix cells in colorectal cancer Homo sapiens
-
SW-620 cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
Matrix metalloproteinase 7
-
 Homo sapiens
MMP7
-
 Homo sapiens

General Information

General Information Comment Organism
evolution the enzyme is a member of a zinc-dependent endopeptidases family (MMPs) Homo sapiens
physiological function the enzyme plays an important role in tumor microenvironment, it decreases the susceptibility to 5-fluorouracil in colon cancer cells Homo sapiens