Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(-)-catechin-3-gallate | inhibition is un affected by presence of 10 mM CaCl2 | Homo sapiens | |
(-)-epicatechin-3-gallate | inhibition is un affected by presence of 10 mM CaCl2 | Homo sapiens | |
(-)-epigallocatechin-3-gallate | inhibitory effect is increased on presence of 10 mM CaCl2, no interaction with Cl- | Homo sapiens | |
(-)-gallocatechin-3-gallate | inhibitory effect is increased on presence of 10 mM CaCl2, no interaction with Cl- | Homo sapiens | |
additional information | green tea catechins inhibit MMP-7 competitively and the galloyl group is essential, differences result from the B-ring, mechanism of inhibition | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzyme from Escherichia coli | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(7-methoxycoumarin-4-yl)-acetyl-Pro-Leu-Gly-Leu-[N-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl]-L-Ala-L-Arg amide + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Matrix metalloproteinase 7 | - |
Homo sapiens |
MMP-7 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8.5 | assay at | Homo sapiens |