Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme expression is upregulated in kidneys that are MHC-incompatible allografts but are tolerated through induction by the administration of anti-donor class II antibodies, as part of the pivotal non-canonical wingless-type signaling pathway, overview | Rattus norvegicus |
Application | Comment | Organism |
---|---|---|
medicine | MMP-7 promotes tolerance of incompatibel allografts and may help in development of strategies to improve long-term graft outcome in transplantation | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | the enzyme is involved in the pivotal wingless-type signaling pathway and in tolerance of MHC-incompatible allografts, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P50280 | LEW.1A and LEW.1W rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | expression analysis in hearts after transplantation, overview | Rattus norvegicus | - |
kidney | expression analysis in kidneys after transplantation, overview | Rattus norvegicus | - |
vascular smooth muscle cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is involved in the pivotal wingless-type signaling pathway and in tolerance of MHC-incompatible allografts, overview | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Matrix metalloproteinase 7 | - |
Rattus norvegicus |
MMP7 | - |
Rattus norvegicus |