Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | infections with Helicobacter pylori increases MMP-7 expression in the stomach epithelium, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Collagen + H2O | Homo sapiens | - |
? | - |
? | |
insulin-like growth factor binding protein-5 + H2O | Homo sapiens | in the medium of gastric myofibroblasts, knockdown of IGFBP-5 abolished the myofibroblast proliferation response to MMP-7, overview | ? | - |
? | |
additional information | Homo sapiens | MMP-7 is involved in signaling between epithelial cells and a key stromal cell type, the myofibroblast, via insulin-like growth factor binding protein-5 cleavage and IGF-II release, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P09237 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelium | MMP-7 is uniquely produced in epithelia | Homo sapiens | - |
gastric gland | - |
Homo sapiens | - |
myofibroblast | primary | Homo sapiens | - |
stomach | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Collagen + H2O | - |
Homo sapiens | ? | - |
? | |
insulin-like growth factor binding protein-5 + H2O | - |
Homo sapiens | ? | - |
? | |
insulin-like growth factor binding protein-5 + H2O | in the medium of gastric myofibroblasts, knockdown of IGFBP-5 abolished the myofibroblast proliferation response to MMP-7, overview | Homo sapiens | ? | - |
? | |
additional information | MMP-7 is involved in signaling between epithelial cells and a key stromal cell type, the myofibroblast, via insulin-like growth factor binding protein-5 cleavage and IGF-II release, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Matrix metalloproteinase-7 | - |
Homo sapiens |
MMP-7 | - |
Homo sapiens |