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Literature summary for 3.4.24.23 extracted from

  • Imai, K.; Yokohama, Y.; Nakanishi, I.; Ohuchi, E.; Fujii, Y.; Nakai, N.; Okada, Y.
    Matrix metalloproteinase 7 (matrilysin) from human rectal carcinoma cells. Activation of the precursor, interaction with other matrix metalloproteinases and enzymic properties (1995), J. Biol. Chem., 270, 6691-6697.
    View publication on PubMed
Search for more literature for 3.4.24.23

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme may play a role in degradation of extracellular matrix macromolecules in concert with matrix metalloproteinase-1, metalloproteinase-3, and metalloproteinase-9 under pathological conditions ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
inactive zymogen is activated: by 4-aminophenylmercuric acetate, yielding an intermediate form of 21000 MW and an active species of 19000 MW, by stromelysin 1 in a single-step mechanism Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
culture medium secreted by COS cells Homo sapiens
-
rectal carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Elastin + H2O
-
 Homo sapiens ?
-
 ?
Fibronectin + H2O
-
 Homo sapiens ?
-
 ?
Gelatin + H2O type I Homo sapiens ?
-
 ?
Laminin-1 + H2O
-
 Homo sapiens ?
-
 ?
additional information no action on: pro-matrix metalloproteinase 2 and 3 Homo sapiens ?
-
 ?
additional information activates pro-matrix metalloproteinase 9 Homo sapiens ?
-
 ?
additional information enzyme may play a role in degradation of extracellular matrix macromolecules in concert with matrix metalloproteinase-1, metalloproteinase-3, and metalloproteinase-9 under pathological conditions Homo sapiens ?
-
 ?
Pro-matrix metalloproteinase 1 + H2O activation by specific cleavage at the Gln80-Phe81 bond Homo sapiens ?
-
 ?
Proteoglycan + H2O
-
 Homo sapiens ?
-
 ?
Type IV collagen + H2O
-
 Homo sapiens ?
-
 ?