KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | enzyme cleavage site specificity and kinetics, overview | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADAMTS-like protein 1 + H2O | Mus musculus | i.e. punctin-1, an extracellular matrix protein. cooperative processing of ADAMTSL1 by both MMP10 and MMP2, EC 3.4.24.24 | ? | - |
? | |
ADAMTS-like protein 1 + H2O | Mus musculus BALB/c | i.e. punctin-1, an extracellular matrix protein. cooperative processing of ADAMTSL1 by both MMP10 and MMP2, EC 3.4.24.24 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | O55123 | - |
- |
Mus musculus BALB/c | O55123 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
3T3 cell | - |
Mus musculus | - |
fibroblast | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADAMTS-like protein 1 + H2O | i.e. punctin-1, an extracellular matrix protein. cooperative processing of ADAMTSL1 by both MMP10 and MMP2, EC 3.4.24.24 | Mus musculus | ? | - |
? | |
ADAMTS-like protein 1 + H2O | recombinant recombinant human ADAMTSL1 (isoform 1), generation of a 40 kDa N-terminal cleavage fragment, cleavage site is MPYD372.373LYHP | Mus musculus | ? | - |
? | |
ADAMTS-like protein 1 + H2O | i.e. punctin-1, an extracellular matrix protein. cooperative processing of ADAMTSL1 by both MMP10 and MMP2, EC 3.4.24.24 | Mus musculus BALB/c | ? | - |
? | |
ADAMTS-like protein 1 + H2O | recombinant recombinant human ADAMTSL1 (isoform 1), generation of a 40 kDa N-terminal cleavage fragment, cleavage site is MPYD372.373LYHP | Mus musculus BALB/c | ? | - |
? | |
collagen alpha-1(l) + H2O | cleavage site is GPPG993-/-994LAGP | Mus musculus | ? | - |
? | |
collagen alpha-1(l) + H2O | cleavage site is GPPG993-/-994LAGP | Mus musculus BALB/c | ? | - |
? | |
collagen alpha-2(I) + H2O | cleavage sites are GPQG871-/-872LLGA, EPGP902-/-903LGIS and GPAG991-/-992SVGP | Mus musculus | ? | - |
? | |
collagen alpha-2(I) + H2O | cleavage sites are GPQG871-/-872LLGA, EPGP902-/-903LGIS and GPAG991-/-992SVGP | Mus musculus BALB/c | ? | - |
? | |
collagen alpha-2(v) + H2O | cleavage site is GPHG487-/-488IQGP | Mus musculus | ? | - |
? | |
lysyl oxidase + H2O | cleavage site is QVFS050-/-051LLSL | Mus musculus | ? | - |
? | |
lysyl oxidase + H2O | cleavage site is QVFS050-/-051LLSL | Mus musculus BALB/c | ? | - |
? | |
platelet-derived growth factor receptor alpha + H2O | cleavage into two fragments of about 40 and 80 kDa, cleavage site is VPAS416.417ILDL in the extracellular domain | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Matrix metalloproteinase 10 | - |
Mus musculus |
MMP10 | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Mus musculus |
General Information | Comment | Organism |
---|---|---|
metabolism | fibroblast secretome cleavage analysis, analysis of the MMP10 substrate degradome, overview | Mus musculus |
additional information | enzyme cleavage site specificity, overview | Mus musculus |
physiological function | the enzyme performs ectodomain shedding of platelet-derived growth factor receptor alpha as well as sequential processing of type I collagen | Mus musculus |