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Literature summary for 3.4.24.22 extracted from

  • Van Themsche, C.; Alain, T.; Kossakowska, A.E.; Urbanski, S.; Potworowski, E.F.; St-Pierre, Y.
    Stromelysin-2 (matrix metalloproteinase 10) is inducible in lymphoma cells and accelerates the growth of lymphoid tumors in vivo (2004), J. Immunol., 173, 3605-3611.
    View publication on PubMed

Application

Application Comment Organism
medicine enzyme overexpression promotes tumor development Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information mice injected with lymphoma cells constitutively expressing enzyme developed thymic lymphoma more rapidly than those injected with control lymphoma cells Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
164T2 cell lymphoma cell, expression of enzyme is induced upon contact of cell with endothelial cells Mus musculus
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267T2 cell lymphoma cell, expression of enzyme is induced upon contact of cell with endothelial cells. Enzyme expression is also induced following exposure to interleukins IL-4, IL-6, and IL-13, but not IL-1 Mus musculus
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