Literature summary for 3.4.24.19 extracted from

Ge, G.; Zhang, Y.; Steiglitz, B.M.; Greenspan, D.S.
Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains (2006), J. Biol. Chem., 281, 10786-10798.

Search for more literature for 3.4.24.19

Activating Compound

Activating Compound	Comment	Organism	Structure
procollagen C-proteinase enhancer 1	enhances full length BMP1 and not truncated versions missing the most COOH-terminal EGF and CUB domains	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	the most NH2-terminal CUB domain (CUB1) is not required for BMP1 secretion nor is the next CUB domain (CUB2) required for enzymatic activity. Secreted protease domain of BMP1, devoid of CUB or epidermal growth factor-like domains, have procollagen C-proteinase activity and activity for biosynthetic processing of biglycan, the latter with kinetics superior to those of the full-length proteins	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Procollagen type I + H2O	-	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
BMP1	-	Homo sapiens

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Release 2023.1 (January 2023)