Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Homo sapiens | |
actinonin | - |
Homo sapiens | |
batimastat | - |
Homo sapiens | |
captopril | - |
Homo sapiens | |
cystatin C | - |
Homo sapiens | |
EDTA | enzyme binding structure, modelling | Homo sapiens | |
fetuin A | - |
Homo sapiens | |
galardin | enzyme binding structure, modelling | Homo sapiens | |
additional information | analysis of binding sites of human meprins, screening of inhibitors by molecular dynamics simulation study, molecular docking, overview | Homo sapiens | |
Pro-Leu-Gly-hydroxamate | enzyme binding structure, modelling | Homo sapiens | |
Ro-327315 | - |
Homo sapiens | |
TAPI-0 | - |
Homo sapiens | |
TAPI-2 | i.e. tumour necrosis factor alpha protease inhibitor | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | a zinc-dependent metalloprotease | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q16819 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
meprin alpha | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00014 | - |
galardin | pH and temperature not specified in the publication | Homo sapiens | |
0.00053 | - |
Pro-Leu-Gly-hydroxamate | pH and temperature not specified in the publication | Homo sapiens | |
0.74 | - |
captopril | pH and temperature not specified in the publication | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | human meprin alpha is modelled using the template structure of astacin | Homo sapiens |