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Literature summary for 3.4.24.17 extracted from

  • Mirastschijski, U.; Dinesh, N.; Baskaran, S.; Wedekind, D.; Gavrilovic, J.; Murray, M.Y.; Bevan, D.; Kelm, S.
    Novel specific human and mouse stromelysin-1 (MMP-3) and stromelysin-2 (MMP-10) antibodies for biochemical and immunohistochemical analyses (2019), Wound Repair Regen., 27, 309-323 .
    View publication on PubMed

Application

Application Comment Organism
analysis unspecific staining in tissue sections of both animal strains with commercial anti-MMP-3 antibody JM3523 and positive but enzyme unspecific staining with the anti-MMP-3 antibody MAB 548 in both MMP-3 wild-type and MMP-3-deficient mouse skin wounds Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
ectopical overexpression of C-terminally Strep-tagged mouse MMP-3 in HepG2 cells Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information MMP-3 deficient mice are crossed back to a homozygous BL10 background for 10 generations as described above. Male MMP-3 knock-out and BL10 wild-type mice are used for the experimental setting Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Mus musculus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ a zinc metalloproteinase Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus P28862 strain C57BL10.RIIIH2r-Mmp3tm1Mol/Ztm is abbreviated as BL10
-
Mus musculus BL10 P28862 strain C57BL10.RIIIH2r-Mmp3tm1Mol/Ztm is abbreviated as BL10
-

Source Tissue

Source Tissue Comment Organism Textmining
skin unspecific staining in tissue sections of both animal strains with commercial anti-MMP-3 antibody JM3523 and positive but enzyme unspecific staining with the anti-MMP-3 antibody MAB 548 in both MMP-3 wild-type and MMP-3-deficient mouse skin wounds, antibody cross-reactivity due to the extreme similarity between MMP-3 and MMP-10 (EC 3.4.24.22) proteins Mus musculus
-

Synonyms

Synonyms Comment Organism
MMP-3
-
Mus musculus
stromelysin-1
-
Mus musculus

General Information

General Information Comment Organism
additional information unspecific staining in tissue sections of both animal strains with commercial anti-MMP-3 antibody JM3523 and positive but enzyme unspecific staining with the anti-MMP-3 antibody MAB 548 in both MMP-3 wild-type and MMP-3-deficient mouse skin wounds, antibody cross-reactivity due to the extreme similarity between MMP-3 and MMP-10 (EC 3.4.24.22) proteins Mus musculus