Literature summary for 3.4.24.17 extracted from

Sasanelli, R.; Boccarelli, A.; Giordano, D.; Laforgia, M.; Arnesano, F.; Natile, G.; Cardellicchio, C.; Capozzi, M.A.; Coluccia, M.
Platinum complexes can inhibit matrix metalloproteinase activity: platinum-diethyl[(methylsulfinyl)methyl]phosphonate complexes as inhibitors of matrix metalloproteinases 2, 3, 9, and 12 (2007), J. Med. Chem., 50, 3434-3441.

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Inhibitors

Inhibitors	Comment	Organism	Structure
clodronate	-	Homo sapiens
dichloro[[(methylsulfinyl-kappaS)methyl]phosphonate-kappaO'']platinum	-	Homo sapiens
[dimethylpropanedioato(2-)-kappa2O1,O3][[(methylsulfinyl-kappaS)methyl]phosphonate-kappaO''']platinum	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0044	-	-	Homo sapiens	[dimethylpropanedioato(2-)-kappa2O1,O3][[(methylsulfinyl-kappaS)methyl]phosphonate-kappaO''']platinum
0.0053	-	-	Homo sapiens	dichloro[[(methylsulfinyl-kappaS)methyl]phosphonate-kappaO'']platinum
0.3	-	-	Homo sapiens	clodronate

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Release 2023.1 (January 2023)