Any feedback?
Literature summary for 3.4.24.17 extracted from
- Bisphosphonates inhibit stromelysin-1 (MMP-3), matrix metalloelastase (MMP-12), collagenase-3 (MMP-13) and enamelysin (MMP-20), but not urokinase-type plasminogen activator, and diminish invasion and migration of human malignant and endothelial cell lines (2002), Anticancer Drugs, 13, 245-254.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alendronate | - |
Homo sapiens |  |
| bisphosphonate | - |
Homo sapiens | |
| clodronate | - |
Homo sapiens | |
| pamidronate | - |
Homo sapiens | |
| zoledronate | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| beta-casein + H2O | - |
Homo sapiens | ? | - |
? | |
| Fibronectin + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MMP-3 | - |
Homo sapiens |
| stromelysin-1 | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
