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Literature summary for 3.4.24.15 extracted from

  • Thompson, A.; Grueninger-Leitch, F.; Huber, G.; Malherbe, P.
    Expression and characterization of human beta-secretase candidates metalloendopeptidase MP78 and cathepsin D in beta APP-overexpressing cells (1997), Mol. Brain Res., 48, 206-214.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
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Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Purification (Commentary)

Purification (Comment) Organism
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Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amyloid precursor protein-derived substrate spanning the beta-secretase site Ile-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser, cleavage occurs predominantly at Lys-Met and Glu-Phe bonds Homo sapiens peptide fragments
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