Any feedback?
Literature summary for 3.4.24.14 extracted from
- Partial purification and characterization of a neutral protease which cleaves the N-terminal propeptides from procollagen (1978), Biochemistry, 17, 2948-2954.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | - |
Gallus gallus |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | required for maximal activity | Gallus gallus | |
| Mg2+ | - |
Gallus gallus | |
| Mn2+ | - |
Gallus gallus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 320000 | - |
gel filtration | Gallus gallus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| procollagen I + H2O | Gallus gallus | - |
? | - |
? | |
| procollagen II + H2O | Gallus gallus | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | glycoprotein | Gallus gallus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Gallus gallus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| procollagen I + H2O | substrate must be in native state | Gallus gallus | pCCollagen I + oligopeptide | partially processed procollagen containing only the C-propeptides | ? | |
| procollagen I + H2O | - |
Gallus gallus | ? | - |
? | |
| procollagen II + H2O | substrate must be in native state | Gallus gallus | pCCollagen II + oligopeptide | partially processed procollagen containing only the C-propeptides | ? | |
| procollagen II + H2O | - |
Gallus gallus | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
procollagen I | Gallus gallus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | - |
inactive below, procollagen I as substrate | Gallus gallus |
| 6.6 | 8.8 | procollagen I as substrate, 50% of optimum activity at pH 6.6 and pH 8.8 | Gallus gallus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
