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Literature summary for 3.4.24.14 extracted from

  • Tuderman, L.; Prockop, D.J.
    Procollagen N-proteinase. Properties of the enzyme purified from chick embryo tendons (1982), Eur. J. Biochem., 125, 545-549.
    View publication on PubMed
Search for more literature for 3.4.24.14

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline 45% inhibition at 0.1 mM Gallus gallus
2,2'-dipyridyl 57% inhibition at 1 mM Gallus gallus
2-mercaptoethanol 81% inhibition at 1150 mM Gallus gallus
Co2+
-
 Gallus gallus
Cu2+
-
 Gallus gallus
dithiothreitol 77% inhibition at 0.5 mM Gallus gallus
EDTA 100% inhibition at 2.5 mM Gallus gallus
Fe2+
-
 Gallus gallus
Mg2+ 64% inhibition at 5 mM Gallus gallus
Mn2+ 49% inhibition at 5 mM Gallus gallus
Pb2+
-
 Gallus gallus
Zn2+
-
 Gallus gallus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0003 0.0005 pNcollagen I
-
 Gallus gallus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required for maximal activity Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
procollagen I + H2O Gallus gallus
-
 ?
-
 ?
procollagen II + H2O Gallus gallus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Gallus gallus

Source Tissue

Source Tissue Comment Organism Textmining
tendon
-
 Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pNcollagen I + H2O
-
 Gallus gallus ?
-
 ?
procollagen I + H2O not procollagen III Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen I + H2O not procollagen IV Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen I + H2O substrate must be in native state Gallus gallus pCCollagen I + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen I + H2O
-
 Gallus gallus ?
-
 ?
procollagen II + H2O substrate must be in native state Gallus gallus pCCollagen II + oligopeptide partially processed procollagen containing only the C-propeptides ?
procollagen II + H2O
-
 Gallus gallus ?
-
 ?