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Literature summary for 3.4.24.13 extracted from

  • Bek-Thomsen, M.; Poulsen, K.; Kilian, M.
    Occurrence and evolution of the paralogous zinc metalloproteases IgA1 protease, ZmpB, ZmpC, and ZmpD in Streptococcus pneumoniae and related commensal species (2012), mBio, 3, 00303-00312.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ zinc metalloprotease Streptococcus sanguinis
Zn2+ zinc metalloprotease Gemella haemolysans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
human immunoglobulin A1 + H2O Streptococcus sanguinis
-
immunoglobulin Fabalpha + immunoglobulin Fc
-
?
human immunoglobulin A1 + H2O Gemella haemolysans
-
immunoglobulin Fabalpha + immunoglobulin Fc
-
?
additional information Streptococcus sanguinis streptococcal immunglobulin A1 protease does not cleave porcine IgA ?
-
?

Organism

Organism UniProt Comment Textmining
Gemella haemolysans
-
-
-
Streptococcus sanguinis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
human immunoglobulin A1 + H2O
-
Streptococcus sanguinis immunoglobulin Fabalpha + immunoglobulin Fc
-
?
human immunoglobulin A1 + H2O
-
Gemella haemolysans immunoglobulin Fabalpha + immunoglobulin Fc
-
?
additional information streptococcal immunglobulin A1 protease does not cleave porcine IgA Streptococcus sanguinis ?
-
?

Synonyms

Synonyms Comment Organism
IgA1 protease
-
Streptococcus sanguinis
IgA1 protease
-
Gemella haemolysans