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Literature summary for 3.4.24.13 extracted from

  • Takenouchi-Ohkubo, N.; Mortensen, L.M.; Drasbek, K.R.; Kilian, M.; Poulsen, K.
    Horizontal transfer of the immunoglobulin A1 protease gene (iga) from Streptococcus to Gemella haemolysans (2006), Microbiology, 152, 2171-2180.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli as a His-tagged fusion protein Streptococcus mitis
expressed in Escherichia coli as a His-tagged fusion protein Gemella haemolysans

Organism

Organism UniProt Comment Textmining
Gemella haemolysans Q6TL30
-
-
Gemella haemolysans CCUG4815 Q6TL30
-
-
Streptococcus mitis Q4U6L1
-
-
Streptococcus mitis Q4U6L2
-
-
Streptococcus mitis SK564 Q4U6L1
-
-
Streptococcus mitis SK609 Q4U6L2
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
enzyme possesses IgA1-cleaving activity Streptococcus mitis
additional information
-
enzyme possesses IgA1-cleaving activity Gemella haemolysans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
human IgA1 + H2O
-
Streptococcus mitis ?
-
?
human IgA1 + H2O
-
Gemella haemolysans ?
-
?
human IgA1 + H2O
-
Gemella haemolysans CCUG4815 ?
-
?
human IgA1 + H2O
-
Streptococcus mitis SK609 ?
-
?
human IgA1 + H2O
-
Streptococcus mitis SK564 ?
-
?

Synonyms

Synonyms Comment Organism
IgA1 protease
-
Streptococcus mitis
IgA1 protease
-
Gemella haemolysans

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Streptococcus mitis
37
-
assay at Gemella haemolysans

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Streptococcus mitis
7.4
-
assay at Gemella haemolysans