Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Neisseria meningitidis | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
immunoglobulin IgA1 + H2O | Neisseria meningitidis | - |
effector domain of IgA1 + Fab determinants of IgA1 | specific cleavage of hinge region. IgA1 bound to bacterial porin A is masked by the serogroup B polysaccharide capsule and less accessible to degradation. De novo synthesis of enzyme is required for degradation of porin-A-bound IgA1 | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Neisseria meningitidis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
immunoglobulin IgA1 + H2O | - |
Neisseria meningitidis | effector domain of IgA1 + Fab determinants of IgA1 | specific cleavage of hinge region. IgA1 bound to bacterial porin A is masked by the serogroup B polysaccharide capsule and less accessible to degradation. De novo synthesis of enzyme is required for degradation of porin-A-bound IgA1 | ? | |
immunoglobulin IgA1 + H2O | - |
Neisseria meningitidis | effector domain of IgA1 + Fab determinants of IgA1 | specific cleavage of hinge region | ? |