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Literature summary for 3.4.24.11 extracted from
- Reaction of neutral endopeptidase 24.11 (enkephalinase) with arginine reagents (1986), J. Biol. Chem., 261, 8649-8654.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Butanedione | - |
Rattus norvegicus |  |
| Phenylglyoxal | - |
Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.12 | - |
glutaryl-Ala-Ala-Phe-4-methoxy-2-naphthylamine | - |
Rattus norvegicus | |
| 0.25 | - |
benzyloxycarbonyl-Ala-Gly-Leu-Ala | - |
Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyloxycarbonyl-Ala-Gly-Leu-Ala + H2O | - |
Rattus norvegicus | ? | - |
? | |
| glutaryl-Ala-Ala-Phe-4-methoxy-2-naphthylamine + H2O | - |
Rattus norvegicus | ? | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 46.4 | - |
benzyloxycarbonyl-Ala-Gly-Leu-Ala | - |
Rattus norvegicus | |
| 58.2 | - |
glutaryl-Ala-Ala-Phe-4-methoxy-2-naphthylamine | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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