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Literature summary for 3.4.24.11 extracted from
- Mechanisms of toxic smoke inhalation and burn injury: role of neutral endopeptidase and vascular leakage in mice (2009), Toxicol. Mech. Methods, 19, 191-196.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (S)-N-[2-(phosphonomethylamino)-3-(4-biphenylyl)-propionyl]-3-aminopropionic acid | effects of neutral endopeptidase in acute inflammation in the lung are studied using a newly developed murine model of smoke and burn injury using NEP antagonist CGS-24592. Smoke and burn-induced lung injury and inflammation in mice pretreated with CGS-24592 is exacerbated, leading to more plasma extravasation and severe airway inflammation | Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| neprilysin | - |
Mus musculus |
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Release 2023.1 (January 2023)
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