Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | - |
Homo sapiens | 9986 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epidermis | - |
Homo sapiens | - |
renal cell carcinoma cell | - |
Homo sapiens | - |
renal tubule | - |
Homo sapiens | - |
squamous cell carcinoma cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
endopeptidase CD10 | - |
Homo sapiens |
neprilysin | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | CD10, a cell-surface neutral endopetidase, is involved in the maintenance of homeostasis, in neoplastic transformation, and in tumor progression through the enzymatic inactivation of bioactive peptides. CD10 is suggested to function as a tumor-suppressor gene, and to inactivate neuropeptide growth factors implicated in cancer progression | Homo sapiens |
physiological function | molecular interactions between arsenic microcrystals and membrane-bound CD10 to be implicated in arsenic-induced carcinogenesis | Homo sapiens |