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Literature summary for 3.4.23.B8 extracted from

  • Pettit, S.C.; Sanchez, R.; Smith, T.; Wehbie, R.; Derse, D.; Swanstrom, R.
    HIV type 1 protease inhibitors fail to inhibit HTLV-I Gag processing in infected cells (1998), AIDS Res. Hum. Retroviruses, 14, 1007-1014.
    View publication on PubMed
Search for more literature for 3.4.23.B8

Inhibitors

Inhibitors Comment Organism Structure
additional information the HIV type 1 protease inhibitors indinavir, saquinavir, ritonavir, or nelfinavir fail to block processing of HTLV-1 Gag Human T-cell leukemia virus type I

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
HTLV-1 Gag + H2O Human T-cell leukemia virus type I processing of the HTLV-1 Gag protein ?
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Organism

Organism UniProt Comment Textmining
Human T-cell leukemia virus type I
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
gag precursor + H2O HTVL-1 Gag Human T-cell leukemia virus type I ?
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HTLV-1 Gag + H2O processing of the HTLV-1 Gag protein Human T-cell leukemia virus type I ?
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additional information the active site of the HTLV-1 protease may have subtle differences in substrate recognition compared with the HIV-1 protease Human T-cell leukemia virus type I ?
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