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Literature summary for 3.4.23.B8 extracted from

  • Kobayashi, M.; Ohi, Y.; Asano, T.; Hayakawa, T.; Kato, K.; Kakinuma, A.; Hatanaka, M.
    Purification and characterization of human T-cell leukemia virus type I protease produced in Escherichia coli (1991), FEBS Lett., 293, 106-110.
    View publication on PubMed
Search for more literature for 3.4.23.B8

Inhibitors

Inhibitors Comment Organism Structure
pepstatin A
-
 Human T-cell leukemia virus type I
Pro-Gln-Val-[(4S,3S)-4-amino-3-hydroxy-6-methylheptanoic acid]-Ala-Leu
-
 Human T-cell leukemia virus type I

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information the Km-value of the gag protein is dependent on the concentration of (NH4)2SO4 Human T-cell leukemia virus type I
0.47
-
 APQVLPVMHPHG pH 5.3, 37°C Human T-cell leukemia virus type I
0.5
-
 YVEPTAPQVLPVMHP pH 5.0, 37°C Human T-cell leukemia virus type I

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
14400
-
 1 * 14400, SDS-PAGE Human T-cell leukemia virus type I
14400
-
 2 * 14400, SDS-PAGE Human T-cell leukemia virus type I
27000
-
 gel filtration Human T-cell leukemia virus type I

Organism

Organism UniProt Comment Textmining
Human T-cell leukemia virus type I
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Human T-cell leukemia virus type I

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.111
-
-
 Human T-cell leukemia virus type I

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
APQVLF(NO2)VMHPL + H2O
-
 Human T-cell leukemia virus type I ?
-
 ?
APQVLPVMHPHG + H2O
-
 Human T-cell leukemia virus type I APQVL + PVMHPHG
-
 ?
gag precursor + H2O
-
 Human T-cell leukemia virus type I ?
-
 ?
KTKVLVVQPK + H2O
-
 Human T-cell leukemia virus type I KTKVL + VVQPK
-
 ?
YVEPTAPQVLPVMHP + H2O
-
 Human T-cell leukemia virus type I ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 14400, SDS-PAGE Human T-cell leukemia virus type I
monomer 1 * 14400, SDS-PAGE Human T-cell leukemia virus type I

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.085
-
 YVEPTAPQVLPVMHP pH 5.0, 37°C Human T-cell leukemia virus type I

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.017
-
 pepstatin A pH 5.0, 37°C Human T-cell leukemia virus type I