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Literature summary for 3.4.23.B6 extracted from

  • Bauerova-Zabranska, H.; Stokrova, J.; Strisovsky, K.; Hunter, E.; Ruml, T.; Pichova, I.
    The RNA binding G-patch domain in retroviral protease is important for infectivity and D-type morphogenesis of Mason-Pfizer monkey virus (2005), J. Biol. Chem., 280, 42106-42112.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of wild-type and mutant enzymes in Escherichia coli strain BL21(DE3) Mason-Pfizer monkey virus

Protein Variants

Protein Variants Comment Organism
A114R site-directed mutagenesis, the mutation alters the substrate specificity and reduces the enzyme activity and viral infectivity of COS-1 cells Mason-Pfizer monkey virus
N109I/Q115I site-directed mutagenesis, the mutation alters the substrate specificity and reduces the enzyme activity and viral infectivity of COS-1 cells Mason-Pfizer monkey virus
Q115I site-directed mutagenesis, the mutation alters the substrate specificity and reduces the enzyme activity and viral infectivity of COS-1 cells Mason-Pfizer monkey virus

Metals/Ions

Metals/Ions Comment Organism Structure
NaCl activates at 0.3 M Mason-Pfizer monkey virus

Organism

Organism UniProt Comment Textmining
Mason-Pfizer monkey virus
-
M-PMV
-

Synonyms

Synonyms Comment Organism
M-PMV PR
-
Mason-Pfizer monkey virus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Mason-Pfizer monkey virus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.3
-
assay at Mason-Pfizer monkey virus