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Literature summary for 3.4.23.B3 extracted from

  • Eizert, H.; Bander, P.; Bagossi, P.; Sperka, T.; Miklossy, G.; Boross, P.; Weber, I.T.; Toezser, J.
    Amino acid preferences of retroviral proteases for amino-terminal positions in a type 1 cleavage site (2008), J. Virol., 82, 10111-10117.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
equine infectious anemia virus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
VFQNYPIVQ + H2O at P4 position the hydrophobic residues Val, Leu, Phe and Pro are preferred equine infectious anemia virus VFQNY + PIVQ
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VLQNYPIVQ + H2O at P4 position the hydrophobic residues Val, Leu, Phe and Pro are preferred equine infectious anemia virus VLQNY + PIVQ
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VPQNYPIVQ + H2O at P4 position the hydrophobic residues Val, Leu, Phe and Pro are preferred equine infectious anemia virus VPQNY + PIVQ
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VSANYPIVQ + H2O Gln is preferred at position P3. The second-best residue at P3 position is Phe. Gly and Ala are also tolerated equine infectious anemia virus VSANY + PIVQ
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VSFNYPIVQ + H2O Gln is preferred at position P3. The second-best residue at P3 position is Phe. Gly and Ala are also tolerated equine infectious anemia virus VSFNY + PIVQ
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VSGNYPIVQ + H2O Gln is preferred at position P3. The second-best residue at P3 position is Phe. Gly and Ala are also tolerated equine infectious anemia virus VSGNY + PIVQ
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VSQNAPIVQ + H2O Phe, Tyr, Leu or Met, Ala are preferred at position P1 in order of decreasing efficiency equine infectious anemia virus VSQNA + PIVQ
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VSQNFPIVQ + H2O Phe, Tyr, Leu or Met, Ala are preferred at position P1 in order of decreasing efficiency equine infectious anemia virus VSQNF + PIVQ
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VSQNLPIVQ + H2O Phe, Tyr, Leu or Met, Ala are preferred at position P1 in order of decreasing efficiency equine infectious anemia virus VSQNL + PIVQ
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VSQNMPIVQ + H2O Phe, Tyr, Leu or Met, Ala are preferred at position P1 in order of decreasing efficiency equine infectious anemia virus VSQNM + PIVQ
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VSQNYPIVQ + H2O Gln is preferred at position P3. The second-best residue at P3 position is Phe. Gly and Ala are also tolerated equine infectious anemia virus VSQNY + PIVQ
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VSQNYPIVQ + H2O Phe, Tyr, Leu or Met, Ala are preferred at position P1 in order of decreasing efficiency equine infectious anemia virus VSQNY + PIVQ
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VVQNYPIVQ + H2O at P4 position the hydrophobic residues Val, Leu, Phe and Pro are preferred equine infectious anemia virus VVQNY + PIVQ
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