Cloned (Comment) | Organism |
---|---|
expression of the mutant enzyme I54G in Escherichia coli. The wild-type enzyme does not accumulate in Escherichia coli at a level sufficient for purifying enough material to homogeneity for crystallization | equine infectious anemia virus |
Crystallization (Comment) | Organism |
---|---|
complex of the 154G mutant enzyme with the inhibitor HBY-793, hanging-drop vapor diffusion method | equine infectious anemia virus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
HBY-793 | - |
equine infectious anemia virus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | equine infectious anemia virus | the enzyme processes viral polyproteins into functional molecules during replication and it also cleaves viral nucleocapsid protein during infection | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
equine infectious anemia virus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme processes viral polyproteins into functional molecules during replication and it also cleaves viral nucleocapsid protein during infection | equine infectious anemia virus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | the molecule is a dimer in which the monomers are related by a crystallographic twofold axis | equine infectious anemia virus |