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Literature summary for 3.4.23.B2 extracted from

  • Wu, X.; Liu, H.; Xiao, H.; Conway, J.A.; Kappes, J.C.
    Inhibition of human and simian immunodeficiency virus protease function by targeting Vpx-protease-mutant fusion protein into viral particles (1996), J. Virol., 70, 3378-3384.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information fusion of HIV-2-Vpx with an enzymatically defective proteases mutant, PR. The Vpx-PR-mutant fusion protein, Vpx-PRM is expressed and packaged efficiently into simian immunodeficiency virus. VpxPRM specifically inhibits the function of the viral protease Simian immunodeficiency virus

Organism

Organism UniProt Comment Textmining
Simian immunodeficiency virus
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