Literature summary for 3.4.23.B2 extracted from

Black, P.L.; Downs, M.B.; Lewis, M.G.; Ussery, M.A.; Dreyer, G.B.; Petteway, S.R., Jr.; Lambert, D.M.
Antiretroviral activities of protease inhibitors against murine leukemia virus and simian immunodeficiency virus in tissue culture (1993), Antimicrob. Agents Chemother., 37, 71-77.

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Inhibitors

Inhibitors	Comment	Organism	Structure
SFK 107457	IC50: 0.0102	Simian immunodeficiency virus
SFK 108842	IC50: 0.00013	Simian immunodeficiency virus
SFK 108922	IC50: below 0.000077 mM	Simian immunodeficiency virus
SFK 109274	IC50: above 0.02 mM	Simian immunodeficiency virus
SFK 17461	IC50: 0.0048 mM	Simian immunodeficiency virus
SKF 108390	IC50: 0.00063	Simian immunodeficiency virus
SKF 108907	IC50: 0.008 mM	Simian immunodeficiency virus

Organism

Organism	UniProt	Comment	Textmining
Simian immunodeficiency virus	-	-	-

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.000077	-	IC50: below 0.000077 mM	Simian immunodeficiency virus	SFK 108922
0.00013	-	IC50: 0.00013 mM	Simian immunodeficiency virus	SFK 108842
0.00063	-	IC50: 0.00063 mM	Simian immunodeficiency virus	SKF 108390
0.0048	-	IC50: 0.0048 mM	Simian immunodeficiency virus	SFK 17461
0.008	-	IC50: 0.008 mM	Simian immunodeficiency virus	SKF 108907
0.0102	-	IC50: 0.0102 mM	Simian immunodeficiency virus	SFK 107457
0.02	-	IC50: above 0.02 mM	Simian immunodeficiency virus	SFK 109274

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Release 2023.1 (January 2023)