Literature summary for 3.4.23.B1 extracted from

Kim, J.H.; Kim, Y.S.; Choi, Y.D.; Lee, J.S.; Park, C.S.
Utility of napsin A and thyroid transcription factor 1 in differentiating metastatic pulmonary from non-pulmonary adenocarcinoma in pleural effusion (2011), Acta Cytol., 55, 266-270.

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Application

Application	Comment	Organism
medicine	use of napsin A to distinguish between metastatic pulmonary and non-pulmonary adenocarvcinomas in cell blocks prepared from malignant pleural effusions. Napsin A is positive in 83% of pulmonary adenocarcinomas tested, while thyroid transcription factor TTF-1 is positive in 57% of pulmonary adenocarcinomas. All non-pulmonary adenocarcinoas tested are negative for napsin A and TTF-1. Napsin A shows a reactivity in more than 75% of the tumor cells in 82% of the positive cases, whereas TTF-1 shows a reactivity in more than 75% of the tumor cells only in 20% of the positive cases	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

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Release 2023.1 (January 2023)