Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.23.51 extracted from

  • Theodoratou, E.; Paschos, A.; Mintz-Weber, S.; Bock, A.
    Analysis of the cleavage site specificity of the endopeptidase involved in the maturation of the large subunit of hydrogenase 3 from Escherichia coli (2000), Arch. Microbiol., 173, 110-116.
    View publication on PubMed
Search for more literature for 3.4.23.51

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
precursor of the large subunit of hydrogenase 3 + H2O Escherichia coli HycI involved in the C-terminal processing of HycE, the large subunit of the hydrogenase 3 from Escherichia coli ?
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli P0AEV9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
precursor of the large subunit of hydrogenase 3 + H2O HycI involved in the C-terminal processing of HycE, the large subunit of the hydrogenase 3 from Escherichia coli Escherichia coli ?
-
 ?
precursor of the large subunit of hydrogenase 3 + H2O HycI involved in the C-terminal processing of HycE (UniProt: A1AER2), the large subunit of the hydrogenase 3 from Escherichia coli. Mutational alteration of the amino acid residues neighbouring the cleavage site shows that proteolysis still occurs when chemically similar amino acids are exchanged. Processing is blocked in a variant in which the methionine at the C-terminal side is replaced by a glutamate residue. Truncation of the precursor from the C-terminal end renders variants amenable to maturation even when two-thirds of the extension are removed but abolishes proteolysis upon further deletion of a cluster of six basic amino acids. A construct in which the C-terminal extension from the large subunit of the hydrogenase 2 is fused to the mature part of the large subunit of hydrogenase 3 is neither processed by HycI nor by HybD, the endopeptidase specific for the large subunit of hydrogenase 2 Escherichia coli ?
-
 ?

Synonyms

Synonyms Comment Organism
HYCI
-
 Escherichia coli