Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pancreatic acinar cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cathepsin B + H2O | - |
Mus musculus | activated cathepsin B + ? | - |
? | |
additional information | the enzyme does not activate trypsinogen in vitro | Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 30000, mature enzyme, SDS-PAGE | Mus musculus |
? | x * 43000, proenzyme, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
CTSD | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme deletion alters the severity of acute experimental pancreatitis | Mus musculus |
physiological function | the enzyme regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis | Mus musculus |