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Literature summary for 3.4.23.5 extracted from
- Cathepsin D and apoptosis related proteins are elevated in the brain of autistic subjects (2010), Neuroscience, 165, 363-370.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Homo sapiens | 5764 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 29000 | - |
SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Homo sapiens | - |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 29000, SDS-PAGE | Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | cathepsin D is elevated in the frontal cortex, in pyramidal and granule cells of the hippocampus, and in cerebellar neurons of autistic subjects | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | altered activities of cathepsin D in the autistic brain may play an important role in the pathogenesis of autism | Homo sapiens |
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Release 2023.1 (January 2023)
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