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Literature summary for 3.4.23.5 extracted from

  • Karwowska, A.; Roszkowska-Jakimiec, W.; Dabrowska, E.; Gacko, M.; Chlabicz, M.
    The effect of temperature, acidification, and alkalization changes as well as ethanol on salivary cathepsin D activity (2006), Adv. Med. Sci., 51 Suppl 1, 59-61.
    View publication on PubMed
Search for more literature for 3.4.23.5

Inhibitors

Inhibitors Comment Organism Structure
ethanol high-proof alcoholic beverages Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
saliva
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 activity of cathepsin D undergoes inactivation at the temperature of 50-60°C and at pH of 2.0 and pH of 8.0-10.0. Enzyme activity is also decreased by high concentrations of ethanol and high-proof alcoholic beverages Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Hemoglobin + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
cathepsin D
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
20
-
-
 Homo sapiens

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
-
 50
-
 Homo sapiens

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
50 60 inactivation at the temperature of 50-60°C Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4
-
-
 Homo sapiens

pH Range

pH Minimum pH Maximum Comment Organism
3 8
-
 Homo sapiens

pH Stability

pH Stability pH Stability Maximum Comment Organism
2
-
 inactivation at Homo sapiens
8 10 inactivation at Homo sapiens